Anion translocators in rat-heart mitochondria
نویسندگان
چکیده
منابع مشابه
Effect of antihypertensive agents - captopril and nifedipine - on the functional properties of rat heart mitochondria
Objective(s): Investigation of acute effect on cellular bioenergetics provides the opportunity to characterize the possible adverse effects of drugs more comprehensively. This study aimed to investigate the changes in biochemical and biophysical properties of heart mitochondria induced by captopril and nifedipine antihypertensive treatment. Materials and Methods: Male, 12-week-old Wistar rats i...
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The kinetic properties of the adenosine 5’-diphosphate/adenosine 5’-triphosphate (ADP/ATP) translocator from pea (Pisum sativum l.) root plastids were determined by silicone oi l filtering centrifugation and compared with those of spinach (Spinacia oleracea 1.) chloroplasts and pea leaf mitochondria. In addition, the ADP/ATP transporting activities from the above organelles were reconstituted i...
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The function of mitochondria in generation of cellular ATP in the process of oxidative phosphorylation is widely recognised. During the past decades there have been significant advances in our understanding of the functions of mitochondria other than the generation of energy. These include their role in apoptosis, acting as signalling organelles, mammalian development and ageing as well as thei...
متن کاملControl of citric acid cycle activity in rat heart mitochondria.
Rat heart mitochondria were incubated in state 3 (with ADP) or state 4 (without ADP) in the presence of [3J4C]pyruvate, [3J4C]pyruvate plus unlabeled malate, or unlabeled pyruvate plus uniformly labeled [14C]malate. The net accumulation or loss of each intermediate in the citric acid cycle was determined by specific enzyme assays. In addition, the incorporation of radioactivity into cycle inter...
متن کاملAnion transport in heart.
Anion transport proteins in mammalian cells participate in a wide variety of cell and intracellular organelle functions, including regulation of electrical activity, pH, volume, and the transport of osmolites and metabolites, and may even play a role in the control of immunological responses, cell migration, cell proliferation, and differentiation. Although significant progress over the past de...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1971
ISSN: 0014-5793
DOI: 10.1016/0014-5793(71)80432-5